Transcriptomic signature of Bexarotene (Rexinoid LGD1069) on mammary gland from three transgenic mouse mammary cancer models

BACKGROUND: The rexinoid bexarotene (LGD1069, Targretin) is a highly selective retinoid × receptor (RXR) agonist that inhibits the growth of pre-malignant and malignant breast cells. Bexarotene was shown to suppress the development of breast cancer in transgenic mice models without side effects. The...

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Detalles Bibliográficos
Autores principales: Abba, Martin C, Hu, Yuhui, Levy, Carla C, Gaddis, Sally, Kittrell, Frances S, Zhang, Yun, Hill, Jamal, Bissonnette, Reid P, Medina, Daniel, Brown, Powel H, Marcelo Aldaz, C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563021/
https://www.ncbi.nlm.nih.gov/pubmed/18786257
http://dx.doi.org/10.1186/1755-8794-1-40

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