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Depletion of Human Histone H1 Variants Uncovers Specific Roles in Gene Expression and Cell Growth
At least six histone H1 variants exist in somatic mammalian cells that bind to the linker DNA and stabilize the nucleosome particle contributing to higher order chromatin compaction. In addition, H1 seems to be actively involved in the regulation of gene expression. However, it is not well known whe...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563032/ https://www.ncbi.nlm.nih.gov/pubmed/18927631 http://dx.doi.org/10.1371/journal.pgen.1000227 |