Cargando…

Depletion of Human Histone H1 Variants Uncovers Specific Roles in Gene Expression and Cell Growth

At least six histone H1 variants exist in somatic mammalian cells that bind to the linker DNA and stabilize the nucleosome particle contributing to higher order chromatin compaction. In addition, H1 seems to be actively involved in the regulation of gene expression. However, it is not well known whe...

Descripción completa

Detalles Bibliográficos
Autores principales: Sancho, Mónica, Diani, Erika, Beato, Miguel, Jordan, Albert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563032/
https://www.ncbi.nlm.nih.gov/pubmed/18927631
http://dx.doi.org/10.1371/journal.pgen.1000227