Prevention of Cytotoxic T Cell Escape Using a Heteroclitic Subdominant Viral T Cell Determinant

High affinity antigen-specific T cells play a critical role during protective immune responses. Epitope enhancement can elicit more potent T cell responses and can subsequently lead to a stronger memory pool; however, the molecular basis of such enhancement is unclear. We used the consensus peptide-...

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Detalles Bibliográficos
Autores principales: Butler, Noah S., Theodossis, Alex, Webb, Andrew I., Nastovska, Roza, Ramarathinam, Sri Harsha, Dunstone, Michelle A., Rossjohn, Jamie, Purcell, Anthony W., Perlman, Stanley
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563037/
https://www.ncbi.nlm.nih.gov/pubmed/18949029
http://dx.doi.org/10.1371/journal.ppat.1000186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563037/
https://www.ncbi.nlm.nih.gov/pubmed/18949029
http://dx.doi.org/10.1371/journal.ppat.1000186

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