Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

The aryl hydrocarbon receptor (AHR) is known for its role in the adaptive and toxic responses to a large number of environmental contaminants, as well as its role in hepatovascular development. The classical AHR pathway involves ligand binding, nuclear translocation, heterodimerization with the AHR...

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Detalles Bibliográficos
Autores principales: Bunger, Maureen K., Glover, Edward, Moran, Susan M., Walisser, Jacqueline A., Lahvis, Garet P., Hsu, Erin L., Bradfield, Christopher A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Carcinogenicity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563146/
https://www.ncbi.nlm.nih.gov/pubmed/18660548
http://dx.doi.org/10.1093/toxsci/kfn149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563146/
https://www.ncbi.nlm.nih.gov/pubmed/18660548
http://dx.doi.org/10.1093/toxsci/kfn149

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