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Effects of Phosphodiesterase 4 Inhibition on Alveolarization and Hyperoxia Toxicity in Newborn Rats

BACKGROUND: Prolonged neonatal exposure to hyperoxia is associated with high mortality, leukocyte influx in airspaces, and impaired alveolarization. Inhibitors of type 4 phosphodiesterases are potent anti-inflammatory drugs now proposed for lung disorders. The current study was undertaken to determi...

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Detalles Bibliográficos
Autores principales:	Méhats, Céline, Franco-Montoya, Marie-Laure, Boucherat, Olivier, Lopez, Emmanuel, Schmitz, Thomas, Zana, Elodie, Evain-Brion, Danièle, Bourbon, Jacques, Delacourt, Christophe, Jarreau, Pierre-Henri
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563688/ https://www.ncbi.nlm.nih.gov/pubmed/18941502 http://dx.doi.org/10.1371/journal.pone.0003445

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