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Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells

OBJECTIVE: Chronic inflammation in ulcerative colitis is associated with increased risk for colorectal cancer. Its molecular pathway of cancer development is poorly understood. We investigated the role of neutrophil-derived cellular stress in an in vitro model of neutrophils as effectors and colon e...

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Detalles Bibliográficos
Autores principales:	Campregher, C, Luciani, M G, Gasche, C
Formato:	Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2008
Materias:	Colorectal Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564829/ https://www.ncbi.nlm.nih.gov/pubmed/18272544 http://dx.doi.org/10.1136/gut.2007.141556

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