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A chemical-genetic strategy reveals distinct temporal requirements for SAD-1 kinase in neuronal polarization and synapse formation
BACKGROUND: Neurons assemble into a functional network through a sequence of developmental processes including neuronal polarization and synapse formation. In Caenorhabditis elegans, the serine/threonine SAD-1 kinase is essential for proper neuronal polarity and synaptic organization. To determine i...
Autores principales: | Kim, Joanne SM, Lilley, Brendan N, Zhang, Chao, Shokat, Kevan M, Sanes, Joshua R, Zhen, Mei |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564922/ https://www.ncbi.nlm.nih.gov/pubmed/18808695 http://dx.doi.org/10.1186/1749-8104-3-23 |
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