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Mutation screening of CHD5 in melanoma-prone families linked to 1p36 revealed no deleterious coding or splice site changes
BACKGROUND: A subset of cutaneous malignant melanoma and dysplastic nevi (CMM/DN) families is linked to 1p36. To date, no CMM/DN susceptibility gene has been identified at this locus. Data from mouse studies identified chromodomain helicase DNA binding protein 5 (CHD5) as a tumor suppressor affectin...
Autores principales: | Ng, David, Yang, Xiaohong R, Tucker, Margaret A, Goldstein, Alisa M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564952/ https://www.ncbi.nlm.nih.gov/pubmed/18803848 http://dx.doi.org/10.1186/1756-0500-1-86 |
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