The Use of Bromodeoxyuridine-Immunohistochemistry to Identify Transplanted Fetal Brain Tissue

The immunohistochemical detection of the thymidine analog, 5-bromo-2′-deoxyuridine (BrdU) is shown to be a useful and reliable method to positively identify fetal brain transplants in standard histological preparations. This technique offers several advantages over the [(3)H] thymidine autoradiograp...

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Detalles Bibliográficos
Autores principales: Brown, Darlene B., Stanfield, Brent B.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1989
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565004/
https://www.ncbi.nlm.nih.gov/pubmed/2519541
http://dx.doi.org/10.1155/NP.1989.135
Descripción
Sumario:The immunohistochemical detection of the thymidine analog, 5-bromo-2′-deoxyuridine (BrdU) is shown to be a useful and reliable method to positively identify fetal brain transplants in standard histological preparations. This technique offers several advantages over the [(3)H] thymidine autoradiographic method, including being much more rapid and avoiding the use of radionuclides.

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