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New Surgical Approach To Overcome The Inability Of Injured Mammalian Axons To Grow Within Their Environment

We present a new method for creating conditions conducive to axonal growth in injured optic nerves of adult rabbits. The surgical approach consists of making a cavity in the adult rabbit optic nerve, into which a piece of nitrocellulose soaked with conditioned medium originating from regenerating fi...

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Detalles Bibliográficos
Autores principales: Solomon, Arieh, Lavie, Vered, Ben-Bassat, Sjana, Belkin, Michael, Schwartz, Michal
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565098/
https://www.ncbi.nlm.nih.gov/pubmed/1782256
http://dx.doi.org/10.1155/NP.1991.243
Descripción
Sumario:We present a new method for creating conditions conducive to axonal growth in injured optic nerves of adult rabbits. The surgical approach consists of making a cavity in the adult rabbit optic nerve, into which a piece of nitrocellulose soaked with conditioned medium originating from regenerating fish optic nerves is implanted. In addition, daily irradiation (10 days, 5 min, 35 mW) with low energy He-Ne laser is carried out. Such a combined treatment may open a door to neurobiologists and clinicians, hoping to unravel the enigma of mammalian CNS regeneration.