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Fetal Rat Cerebellar Fragment Transplantation into Adult Rat Forebrain Lesion Cavities

Fragments of fetal rat cerebellar tissue were grafted into forebrain cortical lesion cavities of adult rats. After a survival ranging from 12-151 days, no graft was found to fill the cavity completely. Large neurons, occasionally grouped into nests, were identifiable from the 22nd day. Myelinated gr...

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Detalles Bibliográficos
Autores principales: Chopko, Bohdan W., Voneida, Theodore J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565134/
https://www.ncbi.nlm.nih.gov/pubmed/1373955
http://dx.doi.org/10.1155/NP.1992.63
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author Chopko, Bohdan W.
Voneida, Theodore J.
author_facet Chopko, Bohdan W.
Voneida, Theodore J.
author_sort Chopko, Bohdan W.
collection PubMed
description Fragments of fetal rat cerebellar tissue were grafted into forebrain cortical lesion cavities of adult rats. After a survival ranging from 12-151 days, no graft was found to fill the cavity completely. Large neurons, occasionally grouped into nests, were identifiable from the 22nd day. Myelinated graft fibers, first seen at 32 days, failed to enter host brain. Although grafts demonstrated elements resembling cerebellar tissue, overall organization did not resemble that of the cerebellum.
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spelling pubmed-25651342008-10-16 Fetal Rat Cerebellar Fragment Transplantation into Adult Rat Forebrain Lesion Cavities Chopko, Bohdan W. Voneida, Theodore J. J Neural Transplant Plast Article Fragments of fetal rat cerebellar tissue were grafted into forebrain cortical lesion cavities of adult rats. After a survival ranging from 12-151 days, no graft was found to fill the cavity completely. Large neurons, occasionally grouped into nests, were identifiable from the 22nd day. Myelinated graft fibers, first seen at 32 days, failed to enter host brain. Although grafts demonstrated elements resembling cerebellar tissue, overall organization did not resemble that of the cerebellum. Hindawi Publishing Corporation 1992 /pmc/articles/PMC2565134/ /pubmed/1373955 http://dx.doi.org/10.1155/NP.1992.63 Text en Copyright © 1992 .
spellingShingle Article
Chopko, Bohdan W.
Voneida, Theodore J.
Fetal Rat Cerebellar Fragment Transplantation into Adult Rat Forebrain Lesion Cavities
title Fetal Rat Cerebellar Fragment Transplantation into Adult Rat Forebrain Lesion Cavities
title_full Fetal Rat Cerebellar Fragment Transplantation into Adult Rat Forebrain Lesion Cavities
title_fullStr Fetal Rat Cerebellar Fragment Transplantation into Adult Rat Forebrain Lesion Cavities
title_full_unstemmed Fetal Rat Cerebellar Fragment Transplantation into Adult Rat Forebrain Lesion Cavities
title_short Fetal Rat Cerebellar Fragment Transplantation into Adult Rat Forebrain Lesion Cavities
title_sort fetal rat cerebellar fragment transplantation into adult rat forebrain lesion cavities
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565134/
https://www.ncbi.nlm.nih.gov/pubmed/1373955
http://dx.doi.org/10.1155/NP.1992.63
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