Estrogen Receptors are Present in Neocortical Transplants

Fetal neocortical tissue was grafted into neocortical lesion cavities made in newborn rats. After two weeks survival, in vitro binding of [(3)H]- estradiol to cytosolic preparations provided evidence of estrogen receptors within the transplants. The observed high levels correspond to previous work d...

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Detalles Bibliográficos
Autores principales: Pedersen, Erik B., O'Keefe, Joan A., Handa, Robert J., Castro, Anthony J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1992
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565143/
https://www.ncbi.nlm.nih.gov/pubmed/1515481
http://dx.doi.org/10.1155/NP.1992.135
Descripción
Sumario:Fetal neocortical tissue was grafted into neocortical lesion cavities made in newborn rats. After two weeks survival, in vitro binding of [(3)H]- estradiol to cytosolic preparations provided evidence of estrogen receptors within the transplants. The observed high levels correspond to previous work demonstrating elevated estrogen receptor levels during the first postnatal week in the rat cerebral cortex.

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