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Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet
BACKGROUND: Pioglitazone was reported to improve hepatic steatosis and necroinflammation in human studies. To investigate whether the hepato-protective effect of pioglitazone was associated with an improvement of antioxidant defense mechanism, oxidative DNA damage and repair activity were determined...
Autores principales: | Hsiao, Pi-Jung, Hsieh, Tusty-Jiuan, Kuo, Kung-Kai, Hung, Wei-Wen, Tsai, Kun-Bow, Yang, Ching-Hsiu, Yu, Ming-Lung, Shin, Shyi-Jang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565677/ https://www.ncbi.nlm.nih.gov/pubmed/18822121 http://dx.doi.org/10.1186/1471-2199-9-82 |
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