Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus

High levels of serum IgE are considered markers of parasite and helminth exposure. In addition, they are associated with allergic disorders, play a key role in anti-tumoral defence, and are crucial mediators of autoimmune diseases. Total IgE is a strongly heritable trait. In a genome-wide associatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Weidinger, Stephan, Gieger, Christian, Rodriguez, Elke, Baurecht, Hansjörg, Mempel, Martin, Klopp, Norman, Gohlke, Henning, Wagenpfeil, Stefan, Ollert, Markus, Ring, Johannes, Behrendt, Heidrun, Heinrich, Joachim, Novak, Natalija, Bieber, Thomas, Krämer, Ursula, Berdel, Dietrich, von Berg, Andrea, Bauer, Carl Peter, Herbarth, Olf, Koletzko, Sibylle, Prokisch, Holger, Mehta, Divya, Meitinger, Thomas, Depner, Martin, von Mutius, Erika, Liang, Liming, Moffatt, Miriam, Cookson, William, Kabesch, Michael, Wichmann, H.-Erich, Illig, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565692/
https://www.ncbi.nlm.nih.gov/pubmed/18846228
http://dx.doi.org/10.1371/journal.pgen.1000166

Ejemplares similares

Ejemplares similares