HLA Class I-T Cell Epitopes from trans-Sialidase Proteins Reveal Functionally Distinct Subsets of CD8(+) T Cells in Chronic Chagas Disease

BACKGROUND: Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8(+) T cell responses in HLA-A0201(+) individuals chronically infected by T. cruzi. METHODS AND FINDINGS: Herein, we report the identification of peptides encoded by the same trans-sialidase...

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Detalles Bibliográficos
Autores principales: Alvarez, María G., Postan, Miriam, Weatherly, D. Brent, Albareda, María C., Sidney, John, Sette, Alessandro, Olivera, Carina, Armenti, Alejandro H., Tarleton, Rick L., Laucella, Susana A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565697/
https://www.ncbi.nlm.nih.gov/pubmed/18846233
http://dx.doi.org/10.1371/journal.pntd.0000288

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