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Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy

BACKGROUND: Tumor recurrence following radical cystectomy for a low-grade superficial transitional cell carcinoma (TCC) is exceedingly uncommon and has not been reported previously. CASE PRESENTATION: We describe a case of a young male presenting with anorexia, weight loss and a large, painful local...

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Autores principales: Dangle, Pankaj P, Wang, Wenle Paul, Mayerson, Joel, Mortazavi, Amir, Monk, Paul
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566572/
https://www.ncbi.nlm.nih.gov/pubmed/18826578
http://dx.doi.org/10.1186/1477-7819-6-103
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author Dangle, Pankaj P
Wang, Wenle Paul
Mayerson, Joel
Mortazavi, Amir
Monk, Paul
author_facet Dangle, Pankaj P
Wang, Wenle Paul
Mayerson, Joel
Mortazavi, Amir
Monk, Paul
author_sort Dangle, Pankaj P
collection PubMed
description BACKGROUND: Tumor recurrence following radical cystectomy for a low-grade superficial transitional cell carcinoma (TCC) is exceedingly uncommon and has not been reported previously. CASE PRESENTATION: We describe a case of a young male presenting with anorexia, weight loss and a large, painful locally destructive pelvic recurrence, ten years after radical cystoprostatectomy. The pathology was consistent with a low-grade urothelial carcinoma. After an unsuccessful treatment with cisplatin-based chemotherapy, the patient underwent a curative intent hemipelvectomy with complete excision of tumor and is disease free at one year follow-up. CONCLUSION: A literature review related to this unusual presentation is reported and a surgical solutions over chemotherapy and radiotherapy is proposed.
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spelling pubmed-25665722008-10-11 Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy Dangle, Pankaj P Wang, Wenle Paul Mayerson, Joel Mortazavi, Amir Monk, Paul World J Surg Oncol Case Report BACKGROUND: Tumor recurrence following radical cystectomy for a low-grade superficial transitional cell carcinoma (TCC) is exceedingly uncommon and has not been reported previously. CASE PRESENTATION: We describe a case of a young male presenting with anorexia, weight loss and a large, painful locally destructive pelvic recurrence, ten years after radical cystoprostatectomy. The pathology was consistent with a low-grade urothelial carcinoma. After an unsuccessful treatment with cisplatin-based chemotherapy, the patient underwent a curative intent hemipelvectomy with complete excision of tumor and is disease free at one year follow-up. CONCLUSION: A literature review related to this unusual presentation is reported and a surgical solutions over chemotherapy and radiotherapy is proposed. BioMed Central 2008-09-30 /pmc/articles/PMC2566572/ /pubmed/18826578 http://dx.doi.org/10.1186/1477-7819-6-103 Text en Copyright © 2008 Dangle et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dangle, Pankaj P
Wang, Wenle Paul
Mayerson, Joel
Mortazavi, Amir
Monk, Paul
Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy
title Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy
title_full Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy
title_fullStr Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy
title_full_unstemmed Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy
title_short Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy
title_sort low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566572/
https://www.ncbi.nlm.nih.gov/pubmed/18826578
http://dx.doi.org/10.1186/1477-7819-6-103
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