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Fetal and Neonatal Nicotine Exposure in Wistar Rats Causes Progressive Pancreatic Mitochondrial Damage and Beta Cell Dysfunction
Nicotine replacement therapy (NRT) is currently recommended as a safe smoking cessation aid for pregnant women. However, fetal and neonatal nicotine exposure in rats causes mitochondrial-mediated beta cell apoptosis at weaning, and adult-onset dysglycemia, which we hypothesize is related to progress...
Autores principales: | Bruin, Jennifer E., Petre, Maria A., Raha, Sandeep, Morrison, Katherine M., Gerstein, Hertzel C., Holloway, Alison C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566598/ https://www.ncbi.nlm.nih.gov/pubmed/18852877 http://dx.doi.org/10.1371/journal.pone.0003371 |
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