M-CSF Signals through the MAPK/ERK Pathway via Sp1 to Induce VEGF Production and Induces Angiogenesis In Vivo

BACKGROUND: M-CSF recruits mononuclear phagocytes which regulate processes such as angiogenesis and metastases in tumors. VEGF is a potent activator of angiogenesis as it promotes endothelial cell proliferation and new blood vessel formation. Previously, we reported that in vitro M-CSF induces the e...

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Detalles Bibliográficos
Autores principales: Curry, Jennifer M., Eubank, Tim D., Roberts, Ryan D., Wang, Yijie, Pore, Nabendu, Maity, Amit, Marsh, Clay B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566603/
https://www.ncbi.nlm.nih.gov/pubmed/18852899
http://dx.doi.org/10.1371/journal.pone.0003405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566603/
https://www.ncbi.nlm.nih.gov/pubmed/18852899
http://dx.doi.org/10.1371/journal.pone.0003405

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