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MyD88 Dependent Signaling Contributes to Protective Host Defense against Burkholderia pseudomallei
BACKGROUND: Toll-like receptors (TLRs) have a central role in the recognition of pathogens and the initiation of the innate immune response. Myeloid differentiation primary-response gene 88 (MyD88) and TIR-domain-containing adaptor protein inducing IFNβ (TRIF) are regarded as the key signaling adapt...
Autores principales: | Wiersinga, W. Joost, Wieland, Catharina W., Roelofs, Joris J. T. H., van der Poll, Tom |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566818/ https://www.ncbi.nlm.nih.gov/pubmed/18946505 http://dx.doi.org/10.1371/journal.pone.0003494 |
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