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Identification of two conserved aspartic acid residues required for DNA digestion by a novel thermophilic Exonuclease VII in Thermotoga maritima

Exonuclease VII was first identified in 1974 as a DNA exonuclease that did not require any divalent cations for activity. Indeed, Escherichia coli ExoVII was identified in partially purified extracts in the presence of EDTA. ExoVII is comprised of two subunits (XseA and XseB) that are highly conserv...

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Detalles Bibliográficos
Autores principales: Larrea, Andres A., Pedroso, Ilene M., Malhotra, Arun, Myers, Richard S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566859/
https://www.ncbi.nlm.nih.gov/pubmed/18812402
http://dx.doi.org/10.1093/nar/gkn588