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Protein–DNA interactions: structural, thermodynamic and clustering patterns of conserved residues in DNA-binding proteins
Amino acid residues, which play important roles in protein function, are often conserved. Here, we analyze thermodynamic and structural data of protein–DNA interactions to explore a relationship between free energy, sequence conservation and structural cooperativity. We observe that the most stabili...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566867/ https://www.ncbi.nlm.nih.gov/pubmed/18801847 http://dx.doi.org/10.1093/nar/gkn573 |