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The whole alignment and nothing but the alignment: the problem of spurious alignment flanks
Pairwise sequence alignment is a ubiquitous tool for inferring the evolution and function of DNA, RNA and protein sequences. It is therefore essential to identify alignments arising by chance alone, i.e. spurious alignments. On one hand, if an entire alignment is spurious, statistical techniques for...
Autores principales: | Frith, Martin C., Park, Yonil, Sheetlin, Sergey L., Spouge, John L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566872/ https://www.ncbi.nlm.nih.gov/pubmed/18796526 http://dx.doi.org/10.1093/nar/gkn579 |
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