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Rigid spin-labeled nucleoside Ç: a nonperturbing EPR probe of nucleic acid conformation

Rigid spin-labeled nucleoside Ç, an analog of deoxycytidine that base-pairs with deoxyguanosine, was incorporated into DNA oligomers by chemical synthesis. Thermal denaturation experiments and circular dichroism (CD) measurements showed that Ç has a negligible effect on DNA duplex stability and conf...

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Detalles Bibliográficos
Autores principales:	Cekan, Pavol, Smith, Alyssa L., Barhate, Nivrutti, Robinson, Bruce H., Sigurdsson, Snorri Th.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566876/ https://www.ncbi.nlm.nih.gov/pubmed/18805908 http://dx.doi.org/10.1093/nar/gkn562

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