Cosegregation of novel mitochondrial 16S rRNA gene mutations with the age-associated T414G variant in human cybrids

Ever increasing evidence has been provided on the accumulation of mutations in the mitochondrial DNA (mtDNA) during the aging process. However, the lack of direct functional consequences of the mutant mtDNA load on the mitochondria-dependent cell metabolism has raised many questions on the physiolog...

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Detalles Bibliográficos
Autores principales: Seibel, Peter, Di Nunno, Chiara, Kukat, Christian, Schäfer, Ingo, Del Bo, Roberto, Bordoni, Andreina, Comi, Giacomo P., Schön, Astrid, Capuano, Ferdinando, Latorre, Dominga, Villani, Gaetano
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566888/
https://www.ncbi.nlm.nih.gov/pubmed/18796524
http://dx.doi.org/10.1093/nar/gkn592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566888/
https://www.ncbi.nlm.nih.gov/pubmed/18796524
http://dx.doi.org/10.1093/nar/gkn592

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