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Inversion of allosteric effect of arginine on N-acetylglutamate synthase, a molecular marker for evolution of tetrapods
BACKGROUND: The efficient conversion of ammonia, a potent neurotoxin, into non-toxic metabolites was an essential adaptation that allowed animals to move from the aquatic to terrestrial biosphere. The urea cycle converts ammonia into urea in mammals, amphibians, turtles, snails, worms and many aquat...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566978/ https://www.ncbi.nlm.nih.gov/pubmed/18801197 http://dx.doi.org/10.1186/1471-2091-9-24 |