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Rapid Interhemispheric Switching during Vocal Production in a Songbird

To generate complex bilateral motor patterns such as those underlying birdsong, neural activity must be highly coordinated across the two cerebral hemispheres. However, it remains largely elusive how this coordination is achieved given that interhemispheric communication between song-control areas i...

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Detalles Bibliográficos
Autores principales: Wang, Claude Z. H, Herbst, Joshua A, Keller, Georg B, Hahnloser, Richard H. R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567002/
https://www.ncbi.nlm.nih.gov/pubmed/18922044
http://dx.doi.org/10.1371/journal.pbio.0060250
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author Wang, Claude Z. H
Herbst, Joshua A
Keller, Georg B
Hahnloser, Richard H. R
author_facet Wang, Claude Z. H
Herbst, Joshua A
Keller, Georg B
Hahnloser, Richard H. R
author_sort Wang, Claude Z. H
collection PubMed
description To generate complex bilateral motor patterns such as those underlying birdsong, neural activity must be highly coordinated across the two cerebral hemispheres. However, it remains largely elusive how this coordination is achieved given that interhemispheric communication between song-control areas in the avian cerebrum is restricted to projections received from bilaterally connecting areas in the mid- and hindbrain. By electrically stimulating cerebral premotor areas in zebra finches, we find that behavioral effectiveness of stimulation rapidly switches between hemispheres. In time intervals in which stimulation in one hemisphere tends to distort songs, stimulation in the other hemisphere is mostly ineffective, revealing an idiosyncratic form of motor dominance that bounces back and forth between hemispheres like a virtual ping-pong ball. The intervals of lateralized effectiveness are broadly distributed and are unrelated to simple spectral and temporal song features. Such interhemispheric switching could be an important dynamical aspect of neural coordination that may have evolved from simpler pattern generator circuits.
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spelling pubmed-25670022008-10-28 Rapid Interhemispheric Switching during Vocal Production in a Songbird Wang, Claude Z. H Herbst, Joshua A Keller, Georg B Hahnloser, Richard H. R PLoS Biol Research Article To generate complex bilateral motor patterns such as those underlying birdsong, neural activity must be highly coordinated across the two cerebral hemispheres. However, it remains largely elusive how this coordination is achieved given that interhemispheric communication between song-control areas in the avian cerebrum is restricted to projections received from bilaterally connecting areas in the mid- and hindbrain. By electrically stimulating cerebral premotor areas in zebra finches, we find that behavioral effectiveness of stimulation rapidly switches between hemispheres. In time intervals in which stimulation in one hemisphere tends to distort songs, stimulation in the other hemisphere is mostly ineffective, revealing an idiosyncratic form of motor dominance that bounces back and forth between hemispheres like a virtual ping-pong ball. The intervals of lateralized effectiveness are broadly distributed and are unrelated to simple spectral and temporal song features. Such interhemispheric switching could be an important dynamical aspect of neural coordination that may have evolved from simpler pattern generator circuits. Public Library of Science 2008-10 2008-10-14 /pmc/articles/PMC2567002/ /pubmed/18922044 http://dx.doi.org/10.1371/journal.pbio.0060250 Text en © 2008 Wang et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Wang, Claude Z. H
Herbst, Joshua A
Keller, Georg B
Hahnloser, Richard H. R
Rapid Interhemispheric Switching during Vocal Production in a Songbird
title Rapid Interhemispheric Switching during Vocal Production in a Songbird
title_full Rapid Interhemispheric Switching during Vocal Production in a Songbird
title_fullStr Rapid Interhemispheric Switching during Vocal Production in a Songbird
title_full_unstemmed Rapid Interhemispheric Switching during Vocal Production in a Songbird
title_short Rapid Interhemispheric Switching during Vocal Production in a Songbird
title_sort rapid interhemispheric switching during vocal production in a songbird
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567002/
https://www.ncbi.nlm.nih.gov/pubmed/18922044
http://dx.doi.org/10.1371/journal.pbio.0060250
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