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‘Self-Protection’ of Individual CD4(+) T Cells against R5 HIV-1 Infection by the Synthesis of Anti-Viral CCR5 Ligands

It is well established that paracrine secretion of anti-viral CCR5 ligands by CD8(+) and CD4(+) T cells can block the infection of activated CD4(+) T cells by R5 and dual-tropic isolates of HIV-1. By contrast, because CD4(+) T cells can be infected by HIV-1 and at least some subsets secrete anti-vir...

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Detalles Bibliográficos
Autores principales: Guan, Yongjun, Abdelwahab, Sayed, Kamin-Lewis, Roberta, DeVico, Anthony L., Lewis, George K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567041/
https://www.ncbi.nlm.nih.gov/pubmed/18941536
http://dx.doi.org/10.1371/journal.pone.0003481