Evolution of Highly Polymorphic T Cell Populations in Siblings with the Wiskott-Aldrich Syndrome

Population level evolutionary processes can occur within a single organism when the germ line contains a mutation that confers a cost at the level of the cell. Here we describe how multiple compensatory mutations arose through a within-individual evolutionary process in two brothers with the immune...

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Detalles Bibliográficos
Autores principales: Lutskiy, Maxim I., Park, Jun Y., Remold, Susanna K., Remold-O'Donnell, Eileen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567846/
https://www.ncbi.nlm.nih.gov/pubmed/18941616
http://dx.doi.org/10.1371/journal.pone.0003444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567846/
https://www.ncbi.nlm.nih.gov/pubmed/18941616
http://dx.doi.org/10.1371/journal.pone.0003444

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