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Evolution of Highly Polymorphic T Cell Populations in Siblings with the Wiskott-Aldrich Syndrome
Population level evolutionary processes can occur within a single organism when the germ line contains a mutation that confers a cost at the level of the cell. Here we describe how multiple compensatory mutations arose through a within-individual evolutionary process in two brothers with the immune...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567846/ https://www.ncbi.nlm.nih.gov/pubmed/18941616 http://dx.doi.org/10.1371/journal.pone.0003444 |