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Shugoshin1 May Play Important Roles in Separation of Homologous Chromosomes and Sister Chromatids during Mouse Oocyte Meiosis

BACKGROUND: Homologous chromosomes separate in meiosis I and sister chromatids separate in meiosis II, generating haploid gametes. To address the question why sister chromatids do not separate in meiosis I, we explored the roles of Shogoshin1 (Sgo1) in chromosome separation during oocyte meiosis. ME...

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Detalles Bibliográficos
Autores principales: Yin, Shen, Ai, Jun-Shu, Shi, Li-Hong, Wei, Liang, Yuan, Ju, Ouyang, Ying-Chun, Hou, Yi, Chen, Da-Yuan, Schatten, Heide, Sun, Qing-Yuan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567865/
https://www.ncbi.nlm.nih.gov/pubmed/18949044
http://dx.doi.org/10.1371/journal.pone.0003516