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Molecular Dynamics Simulations of GABA Binding to the GABA(C) Receptor: The Role of Arg(104)
GABA is the major inhibitory neurotransmitter in the nervous system and acts at a variety of receptors including GABA(C) receptors, which are a subclass of GABA(A) receptors. Here we have used molecular dynamics simulations of GABA docked into the extracellular domain of the GABA(C) receptor to expl...
Autores principales: | Melis, Claudio, Lummis, Sarah C. R., Molteni, Carla |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567930/ https://www.ncbi.nlm.nih.gov/pubmed/18641081 http://dx.doi.org/10.1529/biophysj.107.127589 |
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