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The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor

BACKGROUND: Cyclin D1 is integral for the G1 to S phase of the cell cycle as it regulates cellular proliferation. A polymorphism in cyclin D1, 870 G>A, causes overexpression and supports uncontrollable cellular growth. This polymorphism has been associated with an increased risk of developing man...

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Detalles Bibliográficos
Autores principales: Ashton, Katie A, Proietto, Anthony, Otton, Geoffrey, Symonds, Ian, McEvoy, Mark, Attia, John, Gilbert, Michael, Hamann, Ute, Scott, Rodney J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567988/
https://www.ncbi.nlm.nih.gov/pubmed/18822177
http://dx.doi.org/10.1186/1471-2407-8-272