Cargando…
Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowth, and axon targeting?
The highly polarized architecture of neurons is important for their function. Experimental data based on dominant-negative approaches suggest that the tumor suppressor adenomatous polyposis coli (APC), a regulator of Wnt signaling and the cytoskeleton, regulates polarity of neuroectodermal precursor...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568018/ https://www.ncbi.nlm.nih.gov/pubmed/18852302 http://dx.doi.org/10.1083/jcb.200807079 |