Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release

Neurotransmitter release from presynaptic nerve terminals is regulated by soluble NSF attachment protein receptor (SNARE) complex–mediated synaptic vesicle fusion. Tomosyn inhibits SNARE complex formation and neurotransmitter release by sequestering syntaxin-1 through its C-terminal vesicle-associat...

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Detalles Bibliográficos
Autores principales: Sakisaka, Toshiaki, Yamamoto, Yasunori, Mochida, Sumiko, Nakamura, Michiko, Nishikawa, Kouki, Ishizaki, Hiroyoshi, Okamoto-Tanaka, Miki, Miyoshi, Jun, Fujiyoshi, Yoshinori, Manabe, Toshiya, Takai, Yoshimi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568027/
https://www.ncbi.nlm.nih.gov/pubmed/18936251
http://dx.doi.org/10.1083/jcb.200805150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568027/
https://www.ncbi.nlm.nih.gov/pubmed/18936251
http://dx.doi.org/10.1083/jcb.200805150

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