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Identification of specific histidines as pH sensors in flavivirus membrane fusion
The flavivirus membrane fusion machinery, like that of many other enveloped viruses, is triggered by the acidic pH in endosomes after virus uptake by receptor-mediated endocytosis. It has been hypothesized that conserved histidines in the class II fusion protein E of these viruses function as molecu...
Autores principales: | Fritz, Richard, Stiasny, Karin, Heinz, Franz X. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568029/ https://www.ncbi.nlm.nih.gov/pubmed/18936253 http://dx.doi.org/10.1083/jcb.200806081 |
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