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Dibutyltin Disrupts Glucocorticoid Receptor Function and Impairs Glucocorticoid-Induced Suppression of Cytokine Production

BACKGROUND: Organotins are highly toxic and widely distributed environmental chemicals. Dibutyltin (DBT) is used as stabilizer in the production of polyvinyl chloride plastics, and it is also the major metabolite formed from tributyltin (TBT) in vivo. DBT is immunotoxic, however, the responsible tar...

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Detalles Bibliográficos
Autores principales:	Gumy, Christel, Chandsawangbhuwana, Charlie, Dzyakanchuk, Anna A., Kratschmar, Denise V., Baker, Michael E., Odermatt, Alex
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568824/ https://www.ncbi.nlm.nih.gov/pubmed/18958157 http://dx.doi.org/10.1371/journal.pone.0003545

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