Gene Disruption of Plasmodium falciparum p52 Results in Attenuation of Malaria Liver Stage Development in Cultured Primary Human Hepatocytes

Difficulties with inducing sterile and long lasting protective immunity against malaria with subunit vaccines has renewed interest in vaccinations with attenuated Plasmodium parasites. Immunizations with sporozoites that are attenuated by radiation (RAS) can induce strong protective immunity both in...

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Detalles Bibliográficos
Autores principales: van Schaijk, Ben C. L., Janse, Chris J., van Gemert, Geert-Jan, van Dijk, Melissa R., Gego, Audrey, Franetich, Jean-Francois, van de Vegte-Bolmer, Marga, Yalaoui, Samir, Silvie, Olivier, Hoffman, Stephen L., Waters, Andrew P., Mazier, Dominique, Sauerwein, Robert W., Khan, Shahid M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568858/
https://www.ncbi.nlm.nih.gov/pubmed/18958160
http://dx.doi.org/10.1371/journal.pone.0003549

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