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Sordarin, an antifungal agent with a unique mode of action
The sordarin family of compounds, characterized by a unique tetracyclic diterpene core including a norbornene system, inhibits protein synthesis in fungi by stabilizing the ribosome/EF2 complex. This mode of action is in contrast to typical antifungals, which target the cell membrane. This unusual b...
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| Formato: | Texto |
| Lenguaje: | English |
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Beilstein-Institut
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568878/ https://www.ncbi.nlm.nih.gov/pubmed/18941619 http://dx.doi.org/10.3762/bjoc.4.31 |