The Novel Mouse Mutation Oblivion Inactivates the PMCA2 Pump and Causes Progressive Hearing Loss

Progressive hearing loss is common in the human population, but we have few clues to the molecular basis. Mouse mutants with progressive hearing loss offer valuable insights, and ENU (N-ethyl-N-nitrosourea) mutagenesis is a useful way of generating models. We have characterised a new ENU-induced mou...

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Detalles Bibliográficos
Autores principales: Spiden, Sarah L., Bortolozzi, Mario, Di Leva, Francesca, de Angelis, Martin Hrabé, Fuchs, Helmut, Lim, Dmitry, Ortolano, Saida, Ingham, Neil J., Brini, Marisa, Carafoli, Ernesto, Mammano, Fabio, Steel, Karen P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568954/
https://www.ncbi.nlm.nih.gov/pubmed/18974863
http://dx.doi.org/10.1371/journal.pgen.1000238

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