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Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression
BACKGROUND: It is well known that most neurodegenerative diseases are associated with microglia-mediated inflammation. Our previous research demonstrates that the CD40 signaling is critically involved in microglia-related immune responses in the brain. For example, it is well known that the activati...
Autores principales: | Rezai-Zadeh, Kavon, Ehrhart, Jared, Bai, Yun, Sanberg, Paul R, Bickford, Paula, Tan, Jun, Shytle, R Douglas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569027/ https://www.ncbi.nlm.nih.gov/pubmed/18817573 http://dx.doi.org/10.1186/1742-2094-5-41 |
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