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Postcataract surgery outcome in a series of infants and children with Down syndrome

AIMS: To report the visual and refractive outcome and complications in children with Down syndrome undergoing cataract extraction. METHODS: The case notes of 18 infants and children with lens opacities and Down syndrome who underwent cataract extraction between January 1981 and August 2006 were revi...

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Autores principales: Gardiner, C, Lanigan, B, O’Keefe, M
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569213/
https://www.ncbi.nlm.nih.gov/pubmed/18653605
http://dx.doi.org/10.1136/bjo.2007.134619
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author Gardiner, C
Lanigan, B
O’Keefe, M
author_facet Gardiner, C
Lanigan, B
O’Keefe, M
author_sort Gardiner, C
collection PubMed
description AIMS: To report the visual and refractive outcome and complications in children with Down syndrome undergoing cataract extraction. METHODS: The case notes of 18 infants and children with lens opacities and Down syndrome who underwent cataract extraction between January 1981 and August 2006 were reviewed. RESULTS: Over the 25-year study period, 7% (33 eyes) of paediatric eyes undergoing cataract extraction had Down syndrome. The average follow-up time was 11.2 (SD 7.5) years with a range of 2.5 months to 25 years. 25 were congenital, and eight were developmental lens opacities. 40% of patients attained a postoperative BCVA between 6/9 and 6/18. There was a large myopic shift of −7.96 (4.7) D for aphakes and −8.06 (7.4) D for pseudophakes with an average increase in axial length of 3.58 (3.14) mm. There was a 30% incidence of posterior capsular opacification (PCO) overall, 38% in eyes without a primary posterior capsulotomy. Five eyes developed aphakic glaucoma, one eventually necessitating an enucleation. Two patients had retinal detachments on follow-up. CONCLUSION: Cataract extraction in our population of children with Down syndrome is a safe and effective procedure with a very encouraging visual outcome.
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spelling pubmed-25692132008-10-24 Postcataract surgery outcome in a series of infants and children with Down syndrome Gardiner, C Lanigan, B O’Keefe, M Br J Ophthalmol Original Articles AIMS: To report the visual and refractive outcome and complications in children with Down syndrome undergoing cataract extraction. METHODS: The case notes of 18 infants and children with lens opacities and Down syndrome who underwent cataract extraction between January 1981 and August 2006 were reviewed. RESULTS: Over the 25-year study period, 7% (33 eyes) of paediatric eyes undergoing cataract extraction had Down syndrome. The average follow-up time was 11.2 (SD 7.5) years with a range of 2.5 months to 25 years. 25 were congenital, and eight were developmental lens opacities. 40% of patients attained a postoperative BCVA between 6/9 and 6/18. There was a large myopic shift of −7.96 (4.7) D for aphakes and −8.06 (7.4) D for pseudophakes with an average increase in axial length of 3.58 (3.14) mm. There was a 30% incidence of posterior capsular opacification (PCO) overall, 38% in eyes without a primary posterior capsulotomy. Five eyes developed aphakic glaucoma, one eventually necessitating an enucleation. Two patients had retinal detachments on follow-up. CONCLUSION: Cataract extraction in our population of children with Down syndrome is a safe and effective procedure with a very encouraging visual outcome. BMJ Publishing Group 2008-08 2008-07-24 /pmc/articles/PMC2569213/ /pubmed/18653605 http://dx.doi.org/10.1136/bjo.2007.134619 Text en © Gardiner et al 2008 http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Gardiner, C
Lanigan, B
O’Keefe, M
Postcataract surgery outcome in a series of infants and children with Down syndrome
title Postcataract surgery outcome in a series of infants and children with Down syndrome
title_full Postcataract surgery outcome in a series of infants and children with Down syndrome
title_fullStr Postcataract surgery outcome in a series of infants and children with Down syndrome
title_full_unstemmed Postcataract surgery outcome in a series of infants and children with Down syndrome
title_short Postcataract surgery outcome in a series of infants and children with Down syndrome
title_sort postcataract surgery outcome in a series of infants and children with down syndrome
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569213/
https://www.ncbi.nlm.nih.gov/pubmed/18653605
http://dx.doi.org/10.1136/bjo.2007.134619
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