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Postcataract surgery outcome in a series of infants and children with Down syndrome
AIMS: To report the visual and refractive outcome and complications in children with Down syndrome undergoing cataract extraction. METHODS: The case notes of 18 infants and children with lens opacities and Down syndrome who underwent cataract extraction between January 1981 and August 2006 were revi...
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Formato: | Texto |
Lenguaje: | English |
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BMJ Publishing Group
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569213/ https://www.ncbi.nlm.nih.gov/pubmed/18653605 http://dx.doi.org/10.1136/bjo.2007.134619 |
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author | Gardiner, C Lanigan, B O’Keefe, M |
author_facet | Gardiner, C Lanigan, B O’Keefe, M |
author_sort | Gardiner, C |
collection | PubMed |
description | AIMS: To report the visual and refractive outcome and complications in children with Down syndrome undergoing cataract extraction. METHODS: The case notes of 18 infants and children with lens opacities and Down syndrome who underwent cataract extraction between January 1981 and August 2006 were reviewed. RESULTS: Over the 25-year study period, 7% (33 eyes) of paediatric eyes undergoing cataract extraction had Down syndrome. The average follow-up time was 11.2 (SD 7.5) years with a range of 2.5 months to 25 years. 25 were congenital, and eight were developmental lens opacities. 40% of patients attained a postoperative BCVA between 6/9 and 6/18. There was a large myopic shift of −7.96 (4.7) D for aphakes and −8.06 (7.4) D for pseudophakes with an average increase in axial length of 3.58 (3.14) mm. There was a 30% incidence of posterior capsular opacification (PCO) overall, 38% in eyes without a primary posterior capsulotomy. Five eyes developed aphakic glaucoma, one eventually necessitating an enucleation. Two patients had retinal detachments on follow-up. CONCLUSION: Cataract extraction in our population of children with Down syndrome is a safe and effective procedure with a very encouraging visual outcome. |
format | Text |
id | pubmed-2569213 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-25692132008-10-24 Postcataract surgery outcome in a series of infants and children with Down syndrome Gardiner, C Lanigan, B O’Keefe, M Br J Ophthalmol Original Articles AIMS: To report the visual and refractive outcome and complications in children with Down syndrome undergoing cataract extraction. METHODS: The case notes of 18 infants and children with lens opacities and Down syndrome who underwent cataract extraction between January 1981 and August 2006 were reviewed. RESULTS: Over the 25-year study period, 7% (33 eyes) of paediatric eyes undergoing cataract extraction had Down syndrome. The average follow-up time was 11.2 (SD 7.5) years with a range of 2.5 months to 25 years. 25 were congenital, and eight were developmental lens opacities. 40% of patients attained a postoperative BCVA between 6/9 and 6/18. There was a large myopic shift of −7.96 (4.7) D for aphakes and −8.06 (7.4) D for pseudophakes with an average increase in axial length of 3.58 (3.14) mm. There was a 30% incidence of posterior capsular opacification (PCO) overall, 38% in eyes without a primary posterior capsulotomy. Five eyes developed aphakic glaucoma, one eventually necessitating an enucleation. Two patients had retinal detachments on follow-up. CONCLUSION: Cataract extraction in our population of children with Down syndrome is a safe and effective procedure with a very encouraging visual outcome. BMJ Publishing Group 2008-08 2008-07-24 /pmc/articles/PMC2569213/ /pubmed/18653605 http://dx.doi.org/10.1136/bjo.2007.134619 Text en © Gardiner et al 2008 http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Gardiner, C Lanigan, B O’Keefe, M Postcataract surgery outcome in a series of infants and children with Down syndrome |
title | Postcataract surgery outcome in a series of infants and children with Down syndrome |
title_full | Postcataract surgery outcome in a series of infants and children with Down syndrome |
title_fullStr | Postcataract surgery outcome in a series of infants and children with Down syndrome |
title_full_unstemmed | Postcataract surgery outcome in a series of infants and children with Down syndrome |
title_short | Postcataract surgery outcome in a series of infants and children with Down syndrome |
title_sort | postcataract surgery outcome in a series of infants and children with down syndrome |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569213/ https://www.ncbi.nlm.nih.gov/pubmed/18653605 http://dx.doi.org/10.1136/bjo.2007.134619 |
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