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Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia
In the mammary gland, epithelial cells are embedded in a ‘soft' environment and become functionally differentiated in culture when exposed to a laminin-rich extracellular matrix gel. Here, we define the processes by which mammary epithelial cells integrate biochemical and mechanical extracellul...
Autores principales: | Alcaraz, Jordi, Xu, Ren, Mori, Hidetoshi, Nelson, Celeste M, Mroue, Rana, Spencer, Virginia A, Brownfield, Doug, Radisky, Derek C, Bustamante, Carlos, Bissell, Mina J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569873/ https://www.ncbi.nlm.nih.gov/pubmed/18843297 http://dx.doi.org/10.1038/emboj.2008.206 |
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