Delayed internalization and lack of recycling in a beta(2)-adrenergic receptor fused to the G protein alpha-subunit

BACKGROUND: Chimeric proteins obtained by the fusion of a G protein-coupled receptor (GPCR) sequence to the N-terminus of the G protein α-subunit have been extensively used to investigate several aspects of GPCR signalling. Although both the receptor and the G protein generally maintain a fully func...

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Detalles Bibliográficos
Autores principales: Di Certo, Maria Grazia, Batassa, Enrico M, Casella, Ida, Serafino, Annalucia, Floridi, Aristide, Passananti, Claudio, Molinari, Paola, Mattei, Elisabetta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569931/
https://www.ncbi.nlm.nih.gov/pubmed/18840275
http://dx.doi.org/10.1186/1471-2121-9-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569931/
https://www.ncbi.nlm.nih.gov/pubmed/18840275
http://dx.doi.org/10.1186/1471-2121-9-56

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