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Delayed internalization and lack of recycling in a beta(2)-adrenergic receptor fused to the G protein alpha-subunit
BACKGROUND: Chimeric proteins obtained by the fusion of a G protein-coupled receptor (GPCR) sequence to the N-terminus of the G protein α-subunit have been extensively used to investigate several aspects of GPCR signalling. Although both the receptor and the G protein generally maintain a fully func...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569931/ https://www.ncbi.nlm.nih.gov/pubmed/18840275 http://dx.doi.org/10.1186/1471-2121-9-56 |