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Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones

BACKGROUND: Mycolactones are immunosuppressive and cytotoxic polyketides, comprising five naturally occurring structural variants (named A/B, C, D, E and F), produced by different species of very closely related mycobacteria including the human pathogen, Mycobacterium ulcerans. In M. ulcerans strain...

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Detalles Bibliográficos
Autores principales:	Pidot, Sacha J, Hong, Hui, Seemann, Torsten, Porter, Jessica L, Yip, Marcus J, Men, Artem, Johnson, Matthew, Wilson, Peter, Davies, John K, Leadlay, Peter F, Stinear, Timothy P
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569948/ https://www.ncbi.nlm.nih.gov/pubmed/18840298 http://dx.doi.org/10.1186/1471-2164-9-462

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