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Kinetics of Wnt-Driven β-Catenin Stabilization Revealed by Quantitative and Temporal Imaging
The Wnt/β-catenin signal transduction pathway regulates a broad range of developmental processes. Aberrant activation of the Wnt pathway leads to cancer and degenerative diseases. β-catenin is a key signaling molecule that is frequently used as a direct monitor of Wnt pathway activation. This paper...
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570213/ https://www.ncbi.nlm.nih.gov/pubmed/18941539 http://dx.doi.org/10.1371/journal.pone.0003498 |