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Anti-EGFR Antibody Efficiently and Specifically Inhibits Human TSC2(−)/(−) Smooth Muscle Cell Proliferation. Possible Treatment Options for TSC and LAM

BACKGROUND: Tuberous sclerosis complex (TSC), a tumor syndrome caused by mutations in TSC1 or TSC2 genes, is characterized by the development of hamartomas. We previously isolated, from an angiomyolipoma of a TSC2 patient, a homogenous population of smooth muscle-like cells (TSC2(−/−) ASM cells) tha...

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Detalles Bibliográficos
Autores principales:	Lesma, Elena, Grande, Vera, Ancona, Silvia, Carelli, Stephana, Di Giulio, Anna Maria, Gorio, Alfredo
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570214/ https://www.ncbi.nlm.nih.gov/pubmed/18958173 http://dx.doi.org/10.1371/journal.pone.0003558

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