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The Role of Alpha 6 Integrin in Prostate Cancer Migration and Bone Pain in a Novel Xenograft Model

Of the estimated 565,650 people in the U.S. who will die of cancer in 2008, almost all will have metastasis. Breast, prostate, kidney, thyroid and lung cancers metastasize to the bone. Tumor cells reside within the bone using integrin type cell adhesion receptors and elicit incapacitating bone pain...

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Detalles Bibliográficos
Autores principales: King, Tamara E., Pawar, Sangita C., Majuta, Lisa, Sroka, Isis C., Wynn, Danyel, Demetriou, Manolis C., Nagle, Raymond B., Porreca, Frank, Cress, Anne E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570216/
https://www.ncbi.nlm.nih.gov/pubmed/18958175
http://dx.doi.org/10.1371/journal.pone.0003535