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Orientation of the Calcium Channel β Relative to the α(1)2.2 Subunit Is Critical for Its Regulation of Channel Activity

BACKGROUND: The Ca(v)β subunits of high voltage-activated Ca(2+) channels control the trafficking and biophysical properties of the α(1) subunit. The Ca(v)β-α(1) interaction site has been mapped by crystallographic studies. Nevertheless, how this interaction leads to channel regulation has not been...

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Detalles Bibliográficos
Autores principales:	Vitko, Iuliia, Shcheglovitov, Aleksandr, Baumgart, Joel P., Arias-Olguín, Imilla I., Murbartián, Janet, Arias, Juan Manuel, Perez-Reyes, Edward
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570331/ https://www.ncbi.nlm.nih.gov/pubmed/18958281 http://dx.doi.org/10.1371/journal.pone.0003560

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