Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

OBJECTIVE—A lower in vivo mitochondrial function has been reported in both type 2 diabetic patients and first-degree relatives of type 2 diabetic patients. The nature of this reduction is unknown. Here, we tested the hypothesis that a lower intrinsic mitochondrial respiratory capacity may underlie l...

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Detalles Bibliográficos
Autores principales: Phielix, Esther, Schrauwen-Hinderling, Vera B., Mensink, Marco, Lenaers, Ellen, Meex, Ruth, Hoeks, Joris, Kooi, Marianne Eline, Moonen-Kornips, Esther, Sels, Jean-Pierre, Hesselink, Matthijs K.C., Schrauwen, Patrick
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570390/
https://www.ncbi.nlm.nih.gov/pubmed/18678616
http://dx.doi.org/10.2337/db08-0391

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